Omeprazole
Rank #99 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$182.7M
Total Cost
12,147,266
Total Claims
$182.7M
Total Cost
124,262
Prescribers
$15
Cost per Claim
3,535,079
Beneficiaries
26,873,218
30-Day Fills
$1,470
Avg Cost/Provider
98
Avg Claims/Provider
Share of Medicare Part D Spending
0.07%
of total Medicare Part D spending
$182.7M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $182.7M total
🔎 Data Overview
At $15.00 per prescription, this is an affordable generic medication. Wider use of affordable generics like this could save Medicare billions annually.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Omeprazole
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Dae Rheem | Gastroenterology | Los Angeles, CA | 4,169 | $81K |
| 2 | Alonzo Williams | Gastroenterology | Little Rock, AR | 2,652 | $60K |
| 3 | Christina Frankenfield | Nurse Practitioner | Uniontown, PA | 513 | $53K |
| 4 | Evangeline Emesue | Internal Medicine | Harrisburg, PA | 452 | $51K |
| 5 | Rachel Voeghtly | Nurse Practitioner | Altoona, PA | 403 | $49K |
| 6 | Natalie Brixey | Family Practice | Tishomingo, OK | 464 | $42K |
| 7 | Mitchell Davis | Family Practice | Ada, OK | 458 | $41K |
| 8 | Ashley Theroux | Nurse Practitioner | Haverhill, MA | 1,916 | $40K |
| 9 | Connie Wilson | Emergency Medicine | Ada, OK | 388 | $34K |
| 10 | Carol Carter | Nurse Practitioner | Claremore, OK | 304 | $31K |
| 11 | Rajesh Agarwal | Internal Medicine | Mayfield Heights, OH | 1,725 | $29K |
| 12 | Najmuddin Karimjee | Internal Medicine | Houston, TX | 1,654 | $29K |
| 13 | George Christophi | Gastroenterology | Saint Louis, MO | 1,112 | $28K |
| 14 | Nedal Elass | Family Practice | Kingston, OK | 435 | $28K |
| 15 | Mohammed Rahman | Internal Medicine | Elmhurst, NY | 1,349 | $27K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 96 | Fluticasone Propionate (Fluticasone Propionate) | $187.5M | 5,343,836 |
| 97 | Hydrocodone/Acetaminophen (Hydrocodone-Acetaminophen) | $185.6M | 8,496,609 |
| 98 | Vibegron (Gemtesa) | $185.2M | 283,953 |
| 99 | Omeprazole (Omeprazole) | $182.7M | 12,147,266 |
| 100 | Amlodipine Besylate (Amlodipine Besylate) | $180.1M | 20,835,727 |
| 101 | Dolutegravir Sodium/Lamivudine (Dovato) | $173.3M | 56,930 |
| 102 | Potassium Chloride (Klor-Con M20) | $172.6M | 6,137,143 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology