Dimethyl Fumarate
Rank #147 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$109.8M
Total Cost
29,208
Total Claims
$109.8M
Total Cost
1,312
Prescribers
$3,759
Cost per Claim
412
Beneficiaries
30,906
30-Day Fills
$84K
Avg Cost/Provider
22
Avg Claims/Provider
Share of Medicare Part D Spending
0.04%
of total Medicare Part D spending
$109.8M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $109.8M total
🔎 Data Overview
At $3,759 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $266,501 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Dimethyl Fumarate
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Harold Moses | Neurology | Nashville, TN | 92 | $996K |
| 2 | Scott Silliman | Neuropsychiatry | Jacksonville, FL | 97 | $909K |
| 3 | Jong-Mi Lee | Nurse Practitioner | Stanford, CA | 81 | $786K |
| 4 | Anna Cluskey | Physician Assistant | Milwaukee, WI | 72 | $749K |
| 5 | Erica Grazioli | Neurology | Erie, PA | 77 | $727K |
| 6 | Pamela Clark | Nurse Practitioner | Rochester, NY | 75 | $715K |
| 7 | Malcolm Gottesman | Neurology | East Meadow, NY | 55 | $673K |
| 8 | Mirela Cerghet | Neurology | Detroit, MI | 72 | $664K |
| 9 | Emily Pharr | Neurology | Winston Salem, NC | 55 | $603K |
| 10 | Jacob Sloane | Neurology | Boston, MA | 49 | $603K |
| 11 | Donald Negroski | Neurology | Sarasota, FL | 61 | $578K |
| 12 | Kathleen Harris | Nurse Practitioner | Cleveland, OH | 60 | $576K |
| 13 | Ben Thrower | Neurology | Atlanta, GA | 60 | $573K |
| 14 | Robert Charlson | Neurology | New York, NY | 53 | $560K |
| 15 | Jonathan Howard | Neurology | New York, NY | 42 | $560K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 144 | Erenumab-Aooe (Aimovig Autoinjector) | $111.9M | 118,455 |
| 145 | Corticotropin (Acthar) | $111.6M | 1,633 |
| 146 | Bupropion Hcl (Bupropion Hcl Sr) | $110.0M | 3,323,724 |
| 147 | Dimethyl Fumarate (Dimethyl Fumarate) | $109.8M | 29,208 |
| 148 | Immun Glob G(Igg)/Gly/Iga 0-50 (Gammaplex) | $109.6M | 7,815 |
| 149 | Mesalamine (Mesalamine) | $109.3M | 176,079 |
| 150 | Axitinib (Inlyta) | $109.1M | 5,937 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology