Darunavir/Cobicistat
Brand name: Prezcobix
Rank #158 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$99.7M
Total Cost
38,374
Total Claims
$99.7M
Total Cost
1,184
Prescribers
$2,598
Cost per Claim
1,346
Beneficiaries
40,300
30-Day Fills
$84K
Avg Cost/Provider
32
Avg Claims/Provider
Share of Medicare Part D Spending
0.04%
of total Medicare Part D spending
$99.7M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $99.7M total
🔎 Data Overview
At $2,598 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $74,076 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Darunavir/Cobicistat
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Joseph Gathe | Infectious Disease | Houston, TX | 587 | $1.6M |
| 2 | Sharon Reiley | Nurse Practitioner | Jacksonville, FL | 540 | $1.3M |
| 3 | Natalie Vanek | Infectious Disease | Houston, TX | 329 | $842K |
| 4 | Clayton Barbour | Internal Medicine | Cathedral City, CA | 221 | $619K |
| 5 | Leia Hoang | Pharmacist | San Diego, CA | 86 | $613K |
| 6 | Federico Hinestrosa | Infectious Disease | Orlando, FL | 193 | $488K |
| 7 | Elizabeth Winthrop | Nurse Practitioner | Richmond, VA | 173 | $482K |
| 8 | Daniel Nixon | Infectious Disease | Richmond, VA | 184 | $474K |
| 9 | Judith Bergman | Nurse Practitioner | Phoenix, AZ | 182 | $463K |
| 10 | Stephanie Skipper | Nurse Practitioner | Orlando, FL | 178 | $457K |
| 11 | Gary Cox | Infectious Disease | Durham, NC | 169 | $451K |
| 12 | Noah Lee | Family Practice | Oakland Park, FL | 170 | $443K |
| 13 | Jeena Mathew | Nurse Practitioner | Bartow, FL | 172 | $440K |
| 14 | Aisha Khan | Internal Medicine | Safety Harbor, FL | 178 | $440K |
| 15 | Douglas Taylor | Infectious Disease | East Orange, NJ | 163 | $428K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 155 | Nilotinib Hcl (Tasigna) | $100.9M | 6,308 |
| 156 | Quetiapine Fumarate (Quetiapine Fumarate) | $100.9M | 3,820,737 |
| 157 | Ubrogepant (Ubrelvy) | $100.6M | 75,781 |
| 158 | Darunavir/Cobicistat (Prezcobix) | $99.7M | 38,374 |
| 159 | Tocilizumab (Actemra) | $99.5M | 24,891 |
| 160 | Omalizumab (Xolair) | $98.9M | 30,451 |
| 161 | Brimonidine Tartrate (Alphagan P) | $98.8M | 988,570 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology