Tezepelumab-Ekko
Brand name: Tezspire
Rank #377 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$25.6M
Total Cost
5,900
Total Claims
$25.6M
Total Cost
289
Prescribers
$4,337
Cost per Claim
144
Beneficiaries
5,984
30-Day Fills
$89K
Avg Cost/Provider
20
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$25.6M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $25.6M total
🔎 Data Overview
At $4,337 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $177,678 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Tezepelumab-Ekko
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Karlene Bert | Nurse Practitioner | Modesto, CA | 179 | $773K |
| 2 | Valery Chu | Pharmacist | Brooklyn, NY | 168 | $741K |
| 3 | Anne Marie Holly | Physician Assistant | Rochester, NY | 89 | $391K |
| 4 | Isabel Lee | Nurse Practitioner | Dinuba, CA | 84 | $370K |
| 5 | Kristen Wells | Physician Assistant | Corbin, KY | 76 | $365K |
| 6 | Podduturu Reddy | Internal Medicine | Port Huron, MI | 78 | $322K |
| 7 | Jessica Most | Pulmonary Disease | Philadelphia, PA | 77 | $322K |
| 8 | David Tottori | Allergy/ Immunology | Las Vegas, NV | 77 | $319K |
| 9 | Wendy Gilraine | Nurse Practitioner | Martinsville, VA | 68 | $303K |
| 10 | Yevgeniya Brodskaya | Physician Assistant | Brooklyn, NY | 59 | $270K |
| 11 | Mirna Ayache | Pulmonary Disease | Cleveland, OH | 54 | $264K |
| 12 | Reena Mehta | Allergy/ Immunology | New Orleans, LA | 44 | $240K |
| 13 | Abbas Mansour | Pulmonary Disease | Easley, SC | 55 | $227K |
| 14 | Praveen Akuthota | Pulmonary Disease | San Diego, CA | 45 | $192K |
| 15 | Katherine Johnson | Nurse Practitioner | Knoxville, TN | 47 | $189K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 374 | Perampanel (Fycompa) | $25.9M | 20,876 |
| 375 | Timolol Maleate (Timolol Maleate) | $25.8M | 1,129,537 |
| 376 | Amitriptyline Hcl (Amitriptyline Hcl) | $25.8M | 1,295,043 |
| 377 | Tezepelumab-Ekko (Tezspire) | $25.6M | 5,900 |
| 378 | Ponatinib Hcl (Iclusig) | $25.6M | 1,209 |
| 379 | Citalopram Hydrobromide (Citalopram Hbr) | $25.3M | 2,778,255 |
| 380 | Amoxicillin/Potassium Clav (Amoxicillin-Clavulanate Potass) | $25.3M | 2,207,997 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology