Ozanimod Hydrochloride
Brand name: Zeposia
Rank #491 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$14.2M
Total Cost
1,535
Total Claims
$14.2M
Total Cost
79
Prescribers
$9,265
Cost per Claim
14
Beneficiaries
1,636
30-Day Fills
$180K
Avg Cost/Provider
19
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$14.2M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $14.2M total
🔎 Data Overview
At $9,265 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $180,023 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $1,015,843 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Ozanimod Hydrochloride
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Bruce Hughes | Neurology | Des Moines, IA | 102 | $921K |
| 2 | Edward Gettings | Neurology | Philadelphia, PA | 95 | $799K |
| 3 | Dana Beenstock | Nurse Practitioner | Freehold, NJ | 41 | $512K |
| 4 | Lance Kim | Neurology | Ocala, FL | 54 | $493K |
| 5 | Carrie Downey | Neurology | Bangor, ME | 44 | $413K |
| 6 | Mark Cascione | Neurology | Tampa, FL | 30 | $384K |
| 7 | Barry Vaught | Neurology | Crab Orchard, WV | 36 | $370K |
| 8 | Matthew Baker | Neurology | Naples, FL | 35 | $349K |
| 9 | Anna Cluskey | Physician Assistant | Milwaukee, WI | 37 | $323K |
| 10 | Afif Hentati | Neurology | Evanston, IL | 36 | $321K |
| 11 | Arvo Kanna | Neurology | Newport, TN | 28 | $319K |
| 12 | Aram Zabeti | Neurology | Cincinnati, OH | 35 | $297K |
| 13 | Amanda Thuringer | Neurology | Kansas City, KS | 31 | $271K |
| 14 | Steven Snatic | Neurology | Lafayette, LA | 28 | $247K |
| 15 | Ben Thrower | Neurology | Atlanta, GA | 20 | $220K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 488 | Eteplirsen (Exondys-51) | $14.4M | 192 |
| 489 | Colesevelam Hcl (Colesevelam Hcl) | $14.3M | 50,268 |
| 490 | Bexarotene (Bexarotene) | $14.2M | 1,613 |
| 491 | Ozanimod Hydrochloride (Zeposia) | $14.2M | 1,535 |
| 492 | Enoxaparin Sodium (Enoxaparin Sodium) | $14.2M | 93,202 |
| 493 | Omadacycline Tosylate (Nuzyra) | $14.1M | 1,395 |
| 494 | Binimetinib (Mektovi) | $14.1M | 1,094 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology