Omadacycline Tosylate
Brand name: Nuzyra
Rank #493 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$14.1M
Total Cost
1,395
Total Claims
$14.1M
Total Cost
72
Prescribers
$10K
Cost per Claim
331
Beneficiaries
1,414
30-Day Fills
$197K
Avg Cost/Provider
19
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$14.1M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $14.1M total
🔎 Data Overview
At $10,143 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $196,522 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $42,748 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Omadacycline Tosylate
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Michael Jelinek | Infectious Disease | Edinburg, TX | 47 | $666K |
| 2 | Andrew Dold | Infectious Disease | Dacula, GA | 78 | $633K |
| 3 | Daren Guertin | Podiatry | Baytown, TX | 80 | $613K |
| 4 | Christina Mingora | Pulmonary Disease | Charleston, SC | 39 | $591K |
| 5 | Jared Eddy | Infectious Disease | Denver, CO | 25 | $390K |
| 6 | Fernando Alvarado | Infectious Disease | Altamonte Springs, FL | 36 | $386K |
| 7 | Patrick Flume | Pulmonary Disease | Charleston, SC | 24 | $374K |
| 8 | Yosra Alkabab | Infectious Disease | Charleston, SC | 24 | $319K |
| 9 | Susan Dorman | Infectious Disease | Charleston, SC | 25 | $310K |
| 10 | Kelly Hardesty | Nurse Practitioner | Kouts, IN | 30 | $294K |
| 11 | Laura Glass | Nurse Practitioner | Demopolis, AL | 39 | $289K |
| 12 | Leopoldo Cordova | Infectious Disease | South Miami, FL | 18 | $279K |
| 13 | Stuart Cohen | Infectious Disease | Sacramento, CA | 17 | $263K |
| 14 | Thrissawan Sungkapalee | Infectious Disease | Newport Beach, CA | 11 | $249K |
| 15 | J. Duke | General Surgery | Dothan, AL | 33 | $249K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 490 | Bexarotene (Bexarotene) | $14.2M | 1,613 |
| 491 | Ozanimod Hydrochloride (Zeposia) | $14.2M | 1,535 |
| 492 | Enoxaparin Sodium (Enoxaparin Sodium) | $14.2M | 93,202 |
| 493 | Omadacycline Tosylate (Nuzyra) | $14.1M | 1,395 |
| 494 | Binimetinib (Mektovi) | $14.1M | 1,094 |
| 495 | Glecaprevir/Pibrentasvir (Mavyret) | $14.1M | 1,011 |
| 496 | Pacritinib Citrate (Vonjo) | $13.9M | 626 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology