Lipase/Protease/Amylase
Brand name: Zenpep
Rank #32 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$577.7M
Total Cost
321,809
Total Claims
$577.7M
Total Cost
10,228
Prescribers
$1,795
Cost per Claim
35,393
Beneficiaries
387,590
30-Day Fills
$56K
Avg Cost/Provider
31
Avg Claims/Provider
Share of Medicare Part D Spending
0.21%
of total Medicare Part D spending
$577.7M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $577.7M total
🔎 Data Overview
Ranked #32 out of 500 drugs tracked by total cost. Lipase/Protease/Amylase represents a significant portion of Medicare drug spending.
At $1,795 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $16,323 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Lipase/Protease/Amylase
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | David Franke | Physician Assistant | Laguna Beach, CA | 274 | $2.5M |
| 2 | Yuriy Pertsovsky | Gastroenterology | Brooklyn, NY | 1,000 | $2.4M |
| 3 | Joo Jang | Nurse Practitioner | Leonia, NJ | 893 | $2.0M |
| 4 | Jaesoo Pak | Internal Medicine | Cerritos, CA | 837 | $1.8M |
| 5 | Chang Lee | Internal Medicine | Flushing, NY | 1,656 | $1.7M |
| 6 | Mark Song | Internal Medicine | Los Angeles, CA | 988 | $1.7M |
| 7 | Sonwoo Lee | Internal Medicine | Los Angeles, CA | 1,289 | $1.5M |
| 8 | Mikhail Korogluyev | Osteopathic Manipulative Medicine | Brooklyn, NY | 653 | $1.5M |
| 9 | Weining Liang | Internal Medicine | Flushing, NY | 652 | $1.5M |
| 10 | Soo Kang | Internal Medicine | Buena Park, CA | 1,147 | $1.5M |
| 11 | Jae Yoo | Internal Medicine | Los Angeles, CA | 1,256 | $1.4M |
| 12 | Bahaa Girgis | Internal Medicine | Riverside, CA | 145 | $1.3M |
| 13 | Joann Nguyen | Family Practice | San Jose, CA | 580 | $1.3M |
| 14 | Sang Baik | Internal Medicine | Los Angeles, CA | 1,287 | $1.2M |
| 15 | Joseph Pilewski | Pulmonary Disease | Pittsburgh, PA | 171 | $1.2M |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 29 | Dupilumab (Dupixent Pen) | $609.1M | 156,267 |
| 30 | Rsvpref3 Antigen/As01e/Pf (Arexvy) | $608.6M | 1,935,431 |
| 31 | Pomalidomide (Pomalyst) | $589.0M | 27,253 |
| 32 | Lipase/Protease/Amylase (Zenpep) | $577.7M | 321,809 |
| 33 | Insulin Degludec (Tresiba Flextouch U-100) | $567.8M | 597,178 |
| 34 | Valbenazine Tosylate (Ingrezza) | $553.8M | 73,914 |
| 35 | Fluticasone Propion/Salmeterol (Advair Diskus) | $523.2M | 1,289,942 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology