Dupilumab
Brand name: Dupixent Pen
Rank #29 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$609.1M
Total Cost
156,267
Total Claims
$609.1M
Total Cost
6,392
Prescribers
$3,898
Cost per Claim
3,045
Beneficiaries
160,700
30-Day Fills
$95K
Avg Cost/Provider
24
Avg Claims/Provider
Share of Medicare Part D Spending
0.22%
of total Medicare Part D spending
$609.1M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $609.1M total
🔎 Data Overview
Ranked #29 out of 500 drugs tracked by total cost. Dupilumab represents a significant portion of Medicare drug spending.
At $3,898 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $200,019 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Dupilumab
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | George Drew | Dermatology | Marion, OH | 504 | $2.0M |
| 2 | Jerald Hurdle | Interventional Pain Management | Waterville, ME | 411 | $1.6M |
| 3 | Huachen Wei | Dermatology | Elmhurst, NY | 259 | $1.0M |
| 4 | Nicholas Mollanazar | Dermatology | Philadelphia, PA | 256 | $971K |
| 5 | Craig Wiggins | Nurse Practitioner | Phoenix, AZ | 222 | $865K |
| 6 | Ashok Mittal | Pulmonary Disease | St Petersburg, FL | 219 | $827K |
| 7 | Jason Karp | Pulmonary Disease | Lake Success, NY | 193 | $781K |
| 8 | Kevin Crawford | Dermatology | Seymour, IN | 189 | $735K |
| 9 | Kimberly Wonderlich | Dermatology | Fairbanks, AK | 159 | $716K |
| 10 | Zachary Schwager | Dermatology | Burlington, MA | 168 | $713K |
| 11 | Janiece Feuerstein | Nurse Practitioner | Grand Rapids, MI | 184 | $710K |
| 12 | Huachen Wei | Dermatology | Elmhurst, NY | 183 | $706K |
| 13 | Jessica Most | Pulmonary Disease | Philadelphia, PA | 188 | $681K |
| 14 | Tien Nguyen | Dermatology | Fountain Valley, CA | 176 | $681K |
| 15 | Javier Mendez Ruiz | Allergy/ Immunology | Mayaguez, PR | 163 | $640K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 26 | Cyclosporine (Restasis) | $684.1M | 723,620 |
| 27 | Linaclotide (Linzess) | $639.4M | 823,023 |
| 28 | Insulin Lispro (Humalog Kwikpen U-100) | $623.9M | 854,813 |
| 29 | Dupilumab (Dupixent Pen) | $609.1M | 156,267 |
| 30 | Rsvpref3 Antigen/As01e/Pf (Arexvy) | $608.6M | 1,935,431 |
| 31 | Pomalidomide (Pomalyst) | $589.0M | 27,253 |
| 32 | Lipase/Protease/Amylase (Zenpep) | $577.7M | 321,809 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology