Clozapine

Rank #262 of 500 drugs by total cost

Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026

$47.0M

Total Cost

491,951

Total Claims

$47.0M

Total Cost

8,474

Prescribers

$95

Cost per Claim

14,375

Beneficiaries

493,873

30-Day Fills

$5,542

Avg Cost/Provider

Avg Claims/Provider

Share of Medicare Part D Spending

0.02%

of total Medicare Part D spending

$47.0M of $275.65B

Top 10 prescribers of $47.0M total

#	Provider	Specialty	Location	Claims	Cost
1	Robert Morton	Psychiatry	Ada, OK	10,169	$729K
2	Robert Morton	Psychiatry	Ada, OK	414	$285K
3	Shephali Patel	Psychiatry	Chicago, IL	5,166	$269K
4	Robert Laitman	Nephrology	Bronx, NY	118	$225K
5	Emily Rachal	Nurse Practitioner	Wayne, MI	302	$190K
6	Ramon Garcia	Psychiatry	Sacramento, CA	1,936	$151K
7	Robert Laitman	Nephrology	Bronx, NY	183	$113K
8	Tarrah Holliday	Nurse Practitioner	Atlantic, IA	1,518	$108K
9	Christina Zachar	Psychiatry	Jackson, MI	212	$106K
10	Rex Adamson	Psychiatry	Modesto, CA	202	$102K
11	James Conour	Psychiatry	Portland, OR	1,308	$101K
12	Jeffrey Moffat	Psychiatry	San Bernardino, CA	188	$101K
13	Tshekedi Dennis	Psychiatry	Huntington Beach, CA	371	$100K
14	Malinda Henderson	Nurse Practitioner	Saint Peter, MN	35	$93K
15	Rex Adamson	Psychiatry	Modesto, CA	54	$91K

Top prescribers ranked by total cost for this drug in 2023.

#	Drug	Total Cost	Claims
259	Diroximel Fumarate (Vumerity)	$48.5M	5,351
260	Cabotegravir/Rilpivirine (Cabenuva)	$48.1M	7,384
261	Cenobamate (Xcopri)	$47.6M	33,831
262	Clozapine (Clozapine)	$47.0M	491,951
263	Pembrolizumab (Keytruda)	$46.9M	3,947
264	Glipizide (Glipizide)	$46.9M	2,961,035
265	Losartan/Hydrochlorothiazide (Losartan-Hydrochlorothiazide)	$46.3M	2,039,676

The 20 drugs that cost Medicare the most.

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Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology