Diroximel Fumarate
Brand name: Vumerity
Rank #259 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$48.5M
Total Cost
5,351
Total Claims
$48.5M
Total Cost
260
Prescribers
$9,059
Cost per Claim
15
Beneficiaries
5,563
30-Day Fills
$186K
Avg Cost/Provider
21
Avg Claims/Provider
Share of Medicare Part D Spending
0.02%
of total Medicare Part D spending
$48.5M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $48.5M total
🔎 Data Overview
At $9,059 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $186,434 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $3,231,518 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Diroximel Fumarate
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Amparo Gutierrez | Neurology | Orlando, FL | 100 | $880K |
| 2 | Bruce Hughes | Neurology | Des Moines, IA | 77 | $684K |
| 3 | Jong-Mi Lee | Nurse Practitioner | Stanford, CA | 72 | $673K |
| 4 | Kathleen Harris | Nurse Practitioner | Cleveland, OH | 55 | $551K |
| 5 | Harry Lay | Nurse Practitioner | Raleigh, NC | 56 | $545K |
| 6 | John Hemphill | Neurology | Savannah, GA | 55 | $503K |
| 7 | Mirela Cerghet | Neurology | Detroit, MI | 55 | $500K |
| 8 | Lance Kim | Neurology | Ocala, FL | 56 | $500K |
| 9 | Nestor Ivkov | Neurology | Palos Heights, IL | 56 | $489K |
| 10 | Afif Hentati | Neurology | Evanston, IL | 54 | $471K |
| 11 | Carrie Downey | Neurology | Bangor, ME | 56 | $468K |
| 12 | Allan Perel | Neurology | Staten Island, NY | 55 | $453K |
| 13 | Anil Gulati | Neurology | Chicago, IL | 51 | $453K |
| 14 | Kevin Patel | Neurology | Los Angeles, CA | 48 | $449K |
| 15 | Steven Snatic | Neurology | Lafayette, LA | 49 | $437K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 256 | Donepezil Hcl (Donepezil Hcl) | $50.3M | 3,178,215 |
| 257 | Paliperidone (Paliperidone Er) | $49.3M | 129,516 |
| 258 | Sucralfate (Sucralfate) | $48.5M | 689,007 |
| 259 | Diroximel Fumarate (Vumerity) | $48.5M | 5,351 |
| 260 | Cabotegravir/Rilpivirine (Cabenuva) | $48.1M | 7,384 |
| 261 | Cenobamate (Xcopri) | $47.6M | 33,831 |
| 262 | Clozapine (Clozapine) | $47.0M | 491,951 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology