C1 Esterase Inhibitor, Recomb
Brand name: Ruconest
Rank #498 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$13.8M
Total Cost
155
Total Claims
$13.8M
Total Cost
8
Prescribers
$89K
Cost per Claim
0
Beneficiaries
155
30-Day Fills
$1.7M
Avg Cost/Provider
19
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$13.8M of $275.65B
Top Prescribers by Cost
Top 8 prescribers of $13.8M total
🔎 Data Overview
At $89,188 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $1,728,011 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of C1 Esterase Inhibitor, Recomb
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Mary King | Physician Assistant | Centennial, CO | 46 | $3.9M |
| 2 | Jane Purser | Internal Medicine | Tulsa, OK | 17 | $3.4M |
| 3 | Michael Manning | Allergy/ Immunology | Scottsdale, AZ | 11 | $1.8M |
| 4 | John Anderson | Pulmonary Disease | Homewood, AL | 29 | $1.7M |
| 5 | Huamin Li | Allergy/ Immunology | Wheaton, MD | 13 | $786K |
| 6 | Donald Mcneil | Allergy/ Immunology | Columbus, OH | 13 | $756K |
| 7 | Carly Swint | Physician Assistant | Centennial, CO | 13 | $728K |
| 8 | Jay Kashkin | Pediatric Medicine | Fair Lawn, NJ | 13 | $659K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 495 | Glecaprevir/Pibrentasvir (Mavyret) | $14.1M | 1,011 |
| 496 | Pacritinib Citrate (Vonjo) | $13.9M | 626 |
| 497 | Olmesartan/Hydrochlorothiazide (Olmesartan-Hydrochlorothiazide) | $13.9M | 246,637 |
| 498 | C1 Esterase Inhibitor, Recomb (Ruconest) | $13.8M | 155 |
| 499 | Sildenafil Citrate (Sildenafil Citrate) | $13.8M | 248,961 |
| 500 | Lovastatin (Lovastatin) | $13.6M | 981,262 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology