Berotralstat Hydrochloride
Brand name: Orladeyo
Rank #476 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$15.1M
Total Cost
374
Total Claims
$15.1M
Total Cost
27
Prescribers
$40K
Cost per Claim
0
Beneficiaries
374
30-Day Fills
$557K
Avg Cost/Provider
14
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$15.1M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $15.1M total
🔎 Data Overview
At $40,245 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $557,474 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Berotralstat Hydrochloride
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Mary King | Physician Assistant | Centennial, CO | 28 | $1.1M |
| 2 | Jonathan Bernstein | Allergy/ Immunology | Cincinnati, OH | 22 | $902K |
| 3 | William Micka | Allergy/ Immunology | Springfield, MO | 21 | $827K |
| 4 | Zakir Khan | Internal Medicine | Oneonta, AL | 16 | $639K |
| 5 | Sameer Mathur | Allergy/ Immunology | Madison, WI | 15 | $631K |
| 6 | Donald Mcneil | Allergy/ Immunology | Columbus, OH | 15 | $588K |
| 7 | Neil Amar | Allergy/ Immunology | Waco, TX | 14 | $559K |
| 8 | Rayna Doll | Allergy/ Immunology | Spokane, WA | 14 | $557K |
| 9 | Daniel Suez | Allergy/ Immunology | Irving, TX | 14 | $549K |
| 10 | Tukisa Smith | Allergy/ Immunology | San Diego, CA | 13 | $519K |
| 11 | Edward Nassif | Allergy/ Immunology | Ames, IA | 13 | $519K |
| 12 | Peter Boggs | Allergy/ Immunology | Bossier City, LA | 13 | $519K |
| 13 | Shannon Kearney | Allergy/ Immunology | Bethlehem, PA | 12 | $511K |
| 14 | Walter Ryan | Allergy/ Immunology | Nashua, NH | 13 | $510K |
| 15 | Anna Lang | Allergy/ Immunology | Seattle, WA | 12 | $508K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 473 | Fluocinonide (Fluocinonide) | $15.3M | 217,528 |
| 474 | Diclofenac Potassium (Diclofenac Potassium) | $15.2M | 96,736 |
| 475 | Capmatinib Hydrochloride (Tabrecta) | $15.1M | 824 |
| 476 | Berotralstat Hydrochloride (Orladeyo) | $15.1M | 374 |
| 477 | Lansoprazole (Lansoprazole) | $15.0M | 309,355 |
| 478 | Raloxifene Hcl (Raloxifene Hcl) | $14.8M | 198,063 |
| 479 | Lanthanum Carbonate (Lanthanum Carbonate) | $14.7M | 13,783 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology