Tolvaptan
Brand name: Jynarque
Rank #320 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$34.4M
Total Cost
2,760
Total Claims
$34.4M
Total Cost
174
Prescribers
$12K
Cost per Claim
0
Beneficiaries
2,891
30-Day Fills
$197K
Avg Cost/Provider
16
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$34.4M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $34.4M total
🔎 Data Overview
At $12,447 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $197,438 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Tolvaptan
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | James Evanson | Nephrology | Evansville, IN | 38 | $707K |
| 2 | Michael Brucculeri | Nephrology | Clearwater, FL | 47 | $593K |
| 3 | Osama Amro | Nephrology | Seattle, WA | 30 | $556K |
| 4 | Arzu Hatipoglu | Nephrology | Chalmette, LA | 28 | $522K |
| 5 | Alexander Chang | Nephrology | Danville, PA | 27 | $506K |
| 6 | Mamoon Rasheed | Nephrology | Oklahoma City, OK | 26 | $503K |
| 7 | John Morris | Nephrology | Memphis, TN | 26 | $488K |
| 8 | Douglas Lax | Nephrology | Rockville Centre, NY | 35 | $469K |
| 9 | Michael Fang | Internal Medicine | Downey, CA | 25 | $458K |
| 10 | Imran Dosani | Nephrology | Madisonville, KY | 24 | $442K |
| 11 | Gurmukteshwar Singh | Nephrology | Danville, PA | 24 | $438K |
| 12 | Abeera Mansur | Nephrology | Garden City, KS | 23 | $433K |
| 13 | Imtiaz Islam | Nephrology | Kearney, NE | 22 | $418K |
| 14 | Anthony Tran | Nephrology | Melbourne, FL | 21 | $398K |
| 15 | Paula Duran Sierra | Nephrology | Temple, TX | 22 | $364K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 317 | Trametinib Dimethyl Sulfoxide (Mekinist) | $35.0M | 2,448 |
| 318 | Isosorbide Mononitrate (Isosorbide Mononitrate Er) | $34.5M | 1,805,114 |
| 319 | Clonazepam (Clonazepam) | $34.4M | 3,685,968 |
| 320 | Tolvaptan (Jynarque) | $34.4M | 2,760 |
| 321 | Dalfampridine (Dalfampridine Er) | $34.1M | 40,425 |
| 322 | Olmesartan Medoxomil (Olmesartan Medoxomil) | $33.8M | 1,102,412 |
| 323 | Niraparib Tosylate (Zejula) | $33.7M | 2,206 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology