Pimavanserin Tartrate
Brand name: Nuplazid
Rank #84 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$219.0M
Total Cost
51,053
Total Claims
$219.0M
Total Cost
1,775
Prescribers
$4,291
Cost per Claim
1,569
Beneficiaries
54,213
30-Day Fills
$123K
Avg Cost/Provider
29
Avg Claims/Provider
Share of Medicare Part D Spending
0.08%
of total Medicare Part D spending
$219.0M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $219.0M total
🔎 Data Overview
At $4,291 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $123,405 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $139,607 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Pimavanserin Tartrate
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Rajesh Pahwa | Neurology | Kansas City, KS | 359 | $2.0M |
| 2 | Robert Morton | Psychiatry | Ada, OK | 386 | $1.8M |
| 3 | Sherrie Gould | Nurse Practitioner | La Jolla, CA | 315 | $1.7M |
| 4 | Ilia Itin | Neurology | Cleveland, OH | 312 | $1.6M |
| 5 | Stuart Isaacson | Neurology | Boca Raton, FL | 291 | $1.6M |
| 6 | Kathleen Woschkolup | Neurology | Greenville, SC | 270 | $1.5M |
| 7 | Meredith Hatcher | Physician Assistant | Georgetown, TX | 226 | $1.3M |
| 8 | David Kreitzman | Neurology | Commack, NY | 231 | $1.2M |
| 9 | Jeff Bronstein | Neurology | Los Angeles, CA | 201 | $1.2M |
| 10 | Dolores Stefanski | Nurse Practitioner | Tampa, FL | 241 | $1.1M |
| 11 | Sarah Smith | Physician Assistant | Dallas, TX | 169 | $884K |
| 12 | Charles Kamen | Neurology | Las Vegas, NV | 175 | $880K |
| 13 | Ramsey Falconer | Neurology | Alexandria, VA | 159 | $879K |
| 14 | Lawrence Elmer | Neurology | Toledo, OH | 124 | $853K |
| 15 | George Plotkin | Neurology | Tyler, TX | 162 | $831K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 81 | Emtricitabine/Tenofov Alafenam (Descovy) | $222.4M | 94,580 |
| 82 | Immun Glob G(Igg)/Gly/Iga Ov50 (Gammagard Liquid) | $222.1M | 22,768 |
| 83 | Immun Glob G(Igg)/Pro/Iga 0-50 (Hizentra) | $222.0M | 21,722 |
| 84 | Pimavanserin Tartrate (Nuplazid) | $219.0M | 51,053 |
| 85 | Metformin Hcl (Metformin Hcl) | $218.8M | 14,222,346 |
| 86 | Diclofenac Sodium (Diclofenac Sodium) | $216.8M | 3,418,852 |
| 87 | Abatacept (Orencia) | $216.6M | 36,753 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology