Olanzapine/Samidorphan Malate
Brand name: Lybalvi
Rank #353 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$28.3M
Total Cost
18,294
Total Claims
$28.3M
Total Cost
720
Prescribers
$1,549
Cost per Claim
520
Beneficiaries
18,619
30-Day Fills
$39K
Avg Cost/Provider
25
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$28.3M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $28.3M total
🔎 Data Overview
At $1,549 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $54,487 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Olanzapine/Samidorphan Malate
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Robert Morton | Psychiatry | Ada, OK | 509 | $788K |
| 2 | Laurel Owens | Nurse Practitioner | Lees Summit, MO | 402 | $600K |
| 3 | Vadim Baram | Psychiatry | Saint Louis, MO | 376 | $584K |
| 4 | Tarrah Holliday | Nurse Practitioner | Atlantic, IA | 371 | $545K |
| 5 | Malcolm Duncan | Nurse Practitioner | Austin, TX | 145 | $230K |
| 6 | Shelli Brown | Nurse Practitioner | Atlantic, IA | 135 | $218K |
| 7 | Richard Price | Psychiatry | Monsey, NY | 120 | $196K |
| 8 | Stephen Mack | Nurse Practitioner | Katy, TX | 92 | $193K |
| 9 | Maryrita Mallet | Psychiatry | Weatherford, TX | 121 | $190K |
| 10 | Jahanbakhsh Nasserzare | Psychiatry | North Miami Beach, FL | 112 | $172K |
| 11 | Paul Araullo | Nurse Practitioner | Culver City, CA | 93 | $145K |
| 12 | Daria Lewis | Nurse Practitioner | Cary, NC | 95 | $144K |
| 13 | Melissa Karaffa | Nurse Practitioner | Centralia, IL | 87 | $136K |
| 14 | Victor Ilog | Nurse Practitioner | El Paso, TX | 80 | $135K |
| 15 | Syed Zaidi | Psychiatry | Pinellas Park, FL | 81 | $130K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 350 | Meloxicam (Meloxicam) | $28.6M | 4,714,084 |
| 351 | Triamcinolone Acetonide (Triamcinolone Acetonide) | $28.5M | 2,307,130 |
| 352 | Pitolisant Hcl (Wakix) | $28.4M | 2,361 |
| 353 | Olanzapine/Samidorphan Malate (Lybalvi) | $28.3M | 18,294 |
| 354 | Interferon Beta-1b (Betaseron) | $28.3M | 2,983 |
| 355 | Iloperidone (Fanapt) | $28.2M | 13,925 |
| 356 | Aflibercept (Eylea) | $28.0M | 10,899 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology