Isavuconazonium Sulfate
Brand name: Cresemba
Rank #432 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$19.2M
Total Cost
3,050
Total Claims
$19.2M
Total Cost
157
Prescribers
$6,295
Cost per Claim
109
Beneficiaries
3,237
30-Day Fills
$122K
Avg Cost/Provider
19
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$19.2M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $19.2M total
🔎 Data Overview
At $6,295 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $122,299 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $176,156 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Isavuconazonium Sulfate
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Sofya Tokman | Pulmonary Disease | Phoenix, AZ | 75 | $654K |
| 2 | Ashraf Omar | Pulmonary Disease | Phoenix, AZ | 70 | $634K |
| 3 | Kamyar Afshar | Pulmonary Disease | San Diego, CA | 100 | $610K |
| 4 | Alice Gray | Critical Care (Intensivists) | Aurora, CO | 67 | $534K |
| 5 | Royce Johnson | Infectious Disease | Bakersfield, CA | 70 | $475K |
| 6 | Uriel Sandkovsky | Infectious Disease | Dallas, TX | 67 | $422K |
| 7 | Gordon Yung | Pulmonary Disease | San Diego, CA | 61 | $385K |
| 8 | Reinaldo Rampolla | Pulmonary Disease | West Hollywood, CA | 57 | $349K |
| 9 | Steven Knoper | Pulmonary Disease | Tucson, AZ | 41 | $260K |
| 10 | Adrienne Trentacosti | Physician Assistant | Ann Arbor, MI | 45 | $260K |
| 11 | Aarya Kafi | Critical Care (Intensivists) | San Diego, CA | 41 | $260K |
| 12 | Hilda Diaz | Nurse Practitioner | Los Angeles, CA | 37 | $259K |
| 13 | Amelia Langston | Medical Oncology | Atlanta, GA | 41 | $252K |
| 14 | Erin Medoff | Nurse Practitioner | New Haven, CT | 35 | $236K |
| 15 | Soe Win | Infectious Disease | Bakersfield, CA | 43 | $233K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 429 | Darbepoetin Alfa In Polysorbat (Aranesp) | $19.3M | 6,889 |
| 430 | Ondansetron Hcl (Ondansetron Hcl) | $19.3M | 1,255,548 |
| 431 | Tasimelteon (Hetlioz) | $19.3M | 763 |
| 432 | Isavuconazonium Sulfate (Cresemba) | $19.2M | 3,050 |
| 433 | Paroxetine Hcl (Paroxetine Hcl) | $19.2M | 1,226,222 |
| 434 | Naloxone Hcl (Naloxone Hcl) | $19.0M | 232,875 |
| 435 | Elapegademase-Lvlr (Revcovi) | $19.0M | 52 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology