Esketamine Hcl
Brand name: Spravato
Rank #345 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$29.0M
Total Cost
20,816
Total Claims
$29.0M
Total Cost
393
Prescribers
$1,393
Cost per Claim
353
Beneficiaries
20,822
30-Day Fills
$74K
Avg Cost/Provider
53
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$29.0M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $29.0M total
🔎 Data Overview
At $1,393 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $82,143 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Esketamine Hcl
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Troy Pulas | Psychiatry | Brooksville, FL | 690 | $779K |
| 2 | Julie Zito | Physician Assistant | Waterford, CT | 639 | $754K |
| 3 | Alicia Thomas | Nurse Practitioner | Springfield, MO | 264 | $482K |
| 4 | Jahanbakhsh Nasserzare | Psychiatry | North Miami Beach, FL | 396 | $440K |
| 5 | Abraham Medaris | Psychiatry | Saint Louis, MO | 358 | $388K |
| 6 | Satish Narayan | Psychiatry | Plano, TX | 296 | $371K |
| 7 | Kimberly Kurey | Nurse Practitioner | New London, CT | 314 | $363K |
| 8 | Melissa Reed | Anesthesiology | Seymour, IN | 300 | $354K |
| 9 | Rebecca Harding-Fauth | Nurse Practitioner | Haverhill, MA | 57 | $335K |
| 10 | Margo Fortney | Nurse Practitioner | Brentwood, TN | 89 | $317K |
| 11 | Bradley Sadler | Psychiatry | Mobile, AL | 238 | $306K |
| 12 | Mhd Khaled Bowarshi | Psychiatry | Wesley Chapel, FL | 153 | $300K |
| 13 | David Boguslavsky | Family Practice | Bridgewater, NJ | 228 | $300K |
| 14 | Missy Wu | Physician Assistant | Houston, TX | 273 | $295K |
| 15 | Daniel Loiterstein | Psychiatry | Saint Louis, MO | 256 | $289K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 342 | Hydroxyzine Hcl (Hydroxyzine Hcl) | $30.2M | 1,474,936 |
| 343 | Irbesartan (Irbesartan) | $30.1M | 869,928 |
| 344 | Amiodarone Hcl (Amiodarone Hcl) | $29.9M | 1,007,679 |
| 345 | Esketamine Hcl (Spravato) | $29.0M | 20,816 |
| 346 | Warfarin Sodium (Warfarin Sodium) | $28.9M | 2,126,832 |
| 347 | Ivosidenib (Tibsovo) | $28.9M | 931 |
| 348 | Cyclobenzaprine Hcl (Cyclobenzaprine Hcl) | $28.7M | 2,582,519 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology