Darunavir/Cob/Emtri/Tenof Alaf
Brand name: Symtuza
Rank #103 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$172.5M
Total Cost
34,812
Total Claims
$172.5M
Total Cost
1,037
Prescribers
$4,954
Cost per Claim
1,418
Beneficiaries
35,802
30-Day Fills
$166K
Avg Cost/Provider
34
Avg Claims/Provider
Share of Medicare Part D Spending
0.06%
of total Medicare Part D spending
$172.5M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $172.5M total
🔎 Data Overview
At $4,954 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $166,316 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $121,629 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Darunavir/Cob/Emtri/Tenof Alaf
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Joseph Gathe | Infectious Disease | Houston, TX | 469 | $2.3M |
| 2 | Vitaly Golub | Infectious Disease | Fort Worth, TX | 429 | $2.0M |
| 3 | Sharon Reiley | Nurse Practitioner | Jacksonville, FL | 318 | $1.5M |
| 4 | Noah Lee | Family Practice | Oakland Park, FL | 271 | $1.3M |
| 5 | Marc Johnson | Internal Medicine | Charlotte, NC | 267 | $1.3M |
| 6 | Daniel Brown | Physician Assistant | Ft Lauderdale, FL | 218 | $1.3M |
| 7 | Geeta Manthena | Internal Medicine | Fortworth, TX | 202 | $978K |
| 8 | Ramon Ramirez | Infectious Disease | Tamarac, FL | 189 | $978K |
| 9 | Michael Hiebert | Internal Medicine | Tulsa, OK | 196 | $963K |
| 10 | Anita Scribner | Infectious Disease | Longview, TX | 194 | $959K |
| 11 | Ruben Martinez | Family Practice | Harlingen, TX | 189 | $928K |
| 12 | Sophia Giscombe | Nurse Practitioner | North Palm Beach, FL | 186 | $907K |
| 13 | Jihad Slim | Infectious Disease | Newark, NJ | 171 | $873K |
| 14 | Douglas Taylor | Infectious Disease | East Orange, NJ | 164 | $845K |
| 15 | Brian Beesley | Family Practice | Columbus, OH | 172 | $833K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 100 | Amlodipine Besylate (Amlodipine Besylate) | $180.1M | 20,835,727 |
| 101 | Dolutegravir Sodium/Lamivudine (Dovato) | $173.3M | 56,930 |
| 102 | Potassium Chloride (Klor-Con M20) | $172.6M | 6,137,143 |
| 103 | Darunavir/Cob/Emtri/Tenof Alaf (Symtuza) | $172.5M | 34,812 |
| 104 | Tamsulosin Hcl (Tamsulosin Hcl) | $168.5M | 8,367,036 |
| 105 | Carbidopa/Levodopa (Carbidopa-Levodopa) | $168.3M | 1,361,770 |
| 106 | Duloxetine Hcl (Duloxetine Hcl) | $167.7M | 5,106,690 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology