Cladribine
Brand name: Mavenclad
Rank #444 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$17.5M
Total Cost
228
Total Claims
$17.5M
Total Cost
13
Prescribers
$77K
Cost per Claim
60
Beneficiaries
422
30-Day Fills
$1.3M
Avg Cost/Provider
18
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$17.5M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $17.5M total
🔎 Data Overview
At $76,718 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $1,345,520 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $291,529 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Cladribine
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Amparo Gutierrez | Neurology | Orlando, FL | 41 | $3.2M |
| 2 | Roberto Cruz Saldana | Neurology | Mcallen, TX | 25 | $2.0M |
| 3 | Bruce Hughes | Neurology | Des Moines, IA | 22 | $1.8M |
| 4 | Randall Trudell | Neurology | Knoxville, TN | 21 | $1.7M |
| 5 | Anthony Sharp | Physician Assistant | Oklahoma City, OK | 17 | $1.3M |
| 6 | Donald Negroski | Neurology | Sarasota, FL | 17 | $1.3M |
| 7 | Haylie Day | Nurse Practitioner | Greenbrier, AR | 12 | $964K |
| 8 | Brian Steingo | Neurology | Boca Raton, FL | 13 | $948K |
| 9 | Harold Moses | Neurology | Nashville, TN | 12 | $948K |
| 10 | John Hemphill | Neurology | Savannah, GA | 13 | $934K |
| 11 | Carlos Mora | Neurology | Roanoke, VA | 13 | $832K |
| 12 | Gary Beaver | Neurology | Duluth, MN | 11 | $755K |
| 13 | Ryan Shannon | Nurse Practitioner | Montgomery, AL | 11 | $707K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 441 | Rufinamide (Rufinamide) | $18.0M | 8,793 |
| 442 | Istradefylline (Nourianz) | $17.8M | 7,061 |
| 443 | Encorafenib (Braftovi) | $17.6M | 1,209 |
| 444 | Cladribine (Mavenclad) | $17.5M | 228 |
| 445 | Enalapril Maleate (Enalapril Maleate) | $17.5M | 673,317 |
| 446 | Vismodegib (Erivedge) | $17.4M | 1,317 |
| 447 | Anastrozole (Anastrozole) | $17.4M | 626,025 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology