C1 Esterase Inhibitor
Brand name: Haegarda
Rank #267 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$45.8M
Total Cost
894
Total Claims
$45.8M
Total Cost
46
Prescribers
$51K
Cost per Claim
0
Beneficiaries
894
30-Day Fills
$995K
Avg Cost/Provider
19
Avg Claims/Provider
Share of Medicare Part D Spending
0.02%
of total Medicare Part D spending
$45.8M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $45.8M total
🔎 Data Overview
At $51,190 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $994,868 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of C1 Esterase Inhibitor
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Sean Brady | Allergy/ Immunology | Williamsville, NY | 13 | $5.1M |
| 2 | Aleena Banerji | Allergy/ Immunology | Boston, MA | 13 | $2.5M |
| 3 | Maeve O'connor | Allergy/ Immunology | Charlotte, NC | 18 | $2.4M |
| 4 | Marc Riedl | Allergy/ Immunology | San Diego, CA | 72 | $2.3M |
| 5 | Marc Riedl | Allergy/ Immunology | San Diego, CA | 22 | $1.9M |
| 6 | Douglas Jones | Allergy/ Immunology | Layton, UT | 13 | $1.8M |
| 7 | Joshua Jacobs | Allergy/ Immunology | Walnut Creek, CA | 40 | $1.8M |
| 8 | David Petty | Allergy/ Immunology | Idaho Falls, ID | 13 | $1.8M |
| 9 | Annie Arrey Mensah | Allergy/ Immunology | Farmington Hills, MI | 19 | $1.7M |
| 10 | Jane Purser | Internal Medicine | Tulsa, OK | 55 | $1.4M |
| 11 | Eric Schenkel | Allergy/ Immunology | Bethlehem, PA | 11 | $1.4M |
| 12 | Karen Maltby | Allergy/ Immunology | Tupelo, MS | 14 | $1.2M |
| 13 | Jack Ghably | Allergy/ Immunology | Albuquerque, NM | 13 | $1.0M |
| 14 | Merritt Fajt | Allergy/ Immunology | Pittsburgh, PA | 12 | $998K |
| 15 | Lisa Crandall | Nurse Practitioner | Milwaukee, WI | 22 | $888K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 264 | Glipizide (Glipizide) | $46.9M | 2,961,035 |
| 265 | Losartan/Hydrochlorothiazide (Losartan-Hydrochlorothiazide) | $46.3M | 2,039,676 |
| 266 | Darunavir (Prezista) | $46.0M | 21,793 |
| 267 | C1 Esterase Inhibitor (Haegarda) | $45.8M | 894 |
| 268 | Alectinib Hcl (Alecensa) | $45.7M | 2,686 |
| 269 | Ipratropium Bromide (Ipratropium Bromide) | $45.4M | 656,249 |
| 270 | Amantadine Hcl (Amantadine) | $45.2M | 173,840 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology