Tirzepatide
Brand name: Mounjaro
Rank #17 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$877.9M
Total Cost
680,457
Total Claims
$877.9M
Total Cost
19,800
Prescribers
$1,290
Cost per Claim
73,129
Beneficiaries
800,635
30-Day Fills
$44K
Avg Cost/Provider
34
Avg Claims/Provider
Share of Medicare Part D Spending
0.32%
of total Medicare Part D spending
$877.9M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $877.9M total
🔎 Data Overview
Ranked #17 out of 500 drugs tracked by total cost. Tirzepatide represents a significant portion of Medicare drug spending.
At $1,290 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $12,005 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Tirzepatide
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Gary Reznik | Cardiology | Los Angeles, CA | 1,428 | $1.6M |
| 2 | Iraklii Buziashvili | Endocrinology | Brooklyn, NY | 1,230 | $1.5M |
| 3 | Swarna Varma | Endocrinology | Pittsburgh, PA | 855 | $987K |
| 4 | Julie Jenkins | Nurse Practitioner | Montgomery, AL | 742 | $929K |
| 5 | Megan Kellar | Nurse Practitioner | Sherwood, AR | 680 | $886K |
| 6 | Brian Chou | Endocrinology | Humble, TX | 582 | $862K |
| 7 | Najmuddin Karimjee | Internal Medicine | Houston, TX | 649 | $826K |
| 8 | Rory Breidbart | Endocrinology | Great Neck, NY | 633 | $808K |
| 9 | Vita Anksh | Endocrinology | Naples, FL | 582 | $789K |
| 10 | Matthew Kamil | Endocrinology | Concord, NH | 527 | $769K |
| 11 | Daniel Macias | Endocrinology | Huntington, WV | 607 | $750K |
| 12 | Warda Niaz | Endocrinology | Montgomery, AL | 594 | $711K |
| 13 | Laura Purdy | Family Practice | Calabasas, CA | 579 | $695K |
| 14 | Clifton Jackness | Endocrinology | New York, NY | 473 | $679K |
| 15 | Vasdev Lohano | Endocrinology | Washington, IN | 500 | $675K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 14 | Etanercept (Enbrel Sureclick) | $1.12B | 145,737 |
| 15 | Enzalutamide (Xtandi) | $985.0M | 72,710 |
| 16 | Mirabegron (Myrbetriq) | $927.5M | 1,407,073 |
| 17 | Tirzepatide (Mounjaro) | $877.9M | 680,457 |
| 18 | Ibrutinib (Imbruvica) | $875.8M | 56,368 |
| 19 | Ustekinumab (Stelara) | $852.3M | 31,974 |
| 20 | Paliperidone Palmitate (Invega Sustenna) | $832.3M | 252,388 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology