Sacubitril/Valsartan
Brand name: Entresto
Rank #12 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$1.30B
Total Cost
1,220,812
Total Claims
$1.30B
Total Cost
23,453
Prescribers
$1,066
Cost per Claim
239,316
Beneficiaries
1,994,160
30-Day Fills
$55K
Avg Cost/Provider
52
Avg Claims/Provider
Share of Medicare Part D Spending
0.47%
of total Medicare Part D spending
$1.30B of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $1.30B total
🔎 Data Overview
Ranked #12 out of 500 drugs tracked by total cost. Sacubitril/Valsartan represents a significant portion of Medicare drug spending.
At $1,066 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $5,437 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Sacubitril/Valsartan
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Sohaib Tariq | Cardiology | El Centro, CA | 1,541 | $1.3M |
| 2 | Dannis Hood | Interventional Cardiology | Ringgold, GA | 1,412 | $1.2M |
| 3 | Robert Gordon | Advanced Heart Failure and Transplant Cardiology | Evanston, IL | 838 | $1.2M |
| 4 | Anastasia Nikitina | Cardiology | New York, NY | 1,507 | $1.2M |
| 5 | Kenneth Burnham | Advanced Heart Failure and Transplant Cardiology | Mobile, AL | 1,116 | $1.2M |
| 6 | Gregory Egnaczyk | Advanced Heart Failure and Transplant Cardiology | Cincinnati, OH | 959 | $998K |
| 7 | Dalton Mclean | Advanced Heart Failure and Transplant Cardiology | Greensboro, NC | 951 | $987K |
| 8 | Michael Krueger | Cardiology | Fresno, CA | 619 | $939K |
| 9 | Humberto Machado | Cardiology | Coral Gables, FL | 937 | $930K |
| 10 | Deborah Shipman | Nurse Practitioner | Jonesboro, AR | 973 | $927K |
| 11 | Anna Milstein | Cardiology | Los Angeles, CA | 1,199 | $916K |
| 12 | James Parker | Cardiology | Hammond, LA | 1,049 | $894K |
| 13 | Catherine Marti | Cardiology | Athens, GA | 601 | $882K |
| 14 | Mayer Rashtian | Clinical Cardiac Electrophysiology | Pasadena, CA | 693 | $874K |
| 15 | Leo Polosajian | Cardiology | Reseda, CA | 929 | $855K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 9 | Fluticasone/Umeclidin/Vilanter (Trelegy Ellipta) | $1.81B | 2,046,216 |
| 10 | Dapagliflozin Propanediol (Farxiga) | $1.65B | 1,666,200 |
| 11 | Sitagliptin Phosphate (Januvia) | $1.54B | 1,567,668 |
| 12 | Sacubitril/Valsartan (Entresto) | $1.30B | 1,220,812 |
| 13 | Bictegrav/Emtricit/Tenofov Ala (Biktarvy) | $1.29B | 310,738 |
| 14 | Etanercept (Enbrel Sureclick) | $1.12B | 145,737 |
| 15 | Enzalutamide (Xtandi) | $985.0M | 72,710 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology