Ocrelizumab
Brand name: Ocrevus
Rank #389 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$24.2M
Total Cost
639
Total Claims
$24.2M
Total Cost
26
Prescribers
$38K
Cost per Claim
247
Beneficiaries
3,047
30-Day Fills
$932K
Avg Cost/Provider
25
Avg Claims/Provider
Share of Medicare Part D Spending
0.01%
of total Medicare Part D spending
$24.2M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $24.2M total
🔎 Data Overview
At $37,912 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $931,756 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $98,080 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Ocrelizumab
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Kavita Kalra | Hematology-Oncology | Baltimore, MD | 71 | $2.9M |
| 2 | Jason Silversteen | Neurology | Newark, DE | 61 | $2.4M |
| 3 | Rebecca Rahn | Physician Assistant | Augusta, GA | 46 | $1.9M |
| 4 | John Scagnelli | Neurology | Raleigh, NC | 45 | $1.8M |
| 5 | Amanda Greene | Nurse Practitioner | Ridgeland, MS | 54 | $1.6M |
| 6 | Derek Smith | Neurology | Norwich, CT | 32 | $1.3M |
| 7 | Thomas Scott | Neurology | Pittsburgh, PA | 32 | $1.3M |
| 8 | Neil Lava | Neurology | Atlanta, GA | 35 | $1.2M |
| 9 | Sarah Souza | Nurse Practitioner | North Dartmouth, MA | 21 | $839K |
| 10 | Patricia Melville | Nurse Practitioner | East Setauket, NY | 18 | $726K |
| 11 | Esther Murray | Physician Assistant | Wilmington, NC | 21 | $685K |
| 12 | Patricia Coyle | Neurology | East Setauket, NY | 17 | $672K |
| 13 | Jesus Martinez | Neurology | Memphis, TN | 16 | $664K |
| 14 | John Lindsey | Neurology | Houston, TX | 18 | $643K |
| 15 | Meghan Harris | Neurology | Shreveport, LA | 15 | $561K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 386 | Nitrofurantoin Monohyd/M-Cryst (Nitrofurantoin Mono-Macro) | $24.4M | 1,173,249 |
| 387 | Pegfilgrastim (Neulasta) | $24.4M | 3,096 |
| 388 | Linagliptin/Metformin Hcl (Jentadueto) | $24.3M | 33,018 |
| 389 | Ocrelizumab (Ocrevus) | $24.2M | 639 |
| 390 | Fenofibrate (Fenofibrate) | $24.2M | 670,936 |
| 391 | Empaglifloz/Linaglip/Metformin (Trijardy Xr) | $23.9M | 28,001 |
| 392 | Fluticasone Furoate (Arnuity Ellipta) | $23.7M | 74,825 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology