Mepolizumab
Brand name: Nucala
Rank #174 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$90.1M
Total Cost
20,798
Total Claims
$90.1M
Total Cost
961
Prescribers
$4,331
Cost per Claim
285
Beneficiaries
21,341
30-Day Fills
$94K
Avg Cost/Provider
22
Avg Claims/Provider
Share of Medicare Part D Spending
0.03%
of total Medicare Part D spending
$90.1M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $90.1M total
🔎 Data Overview
At $4,331 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $316,053 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Mepolizumab
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Anne Marie Holly | Physician Assistant | Rochester, NY | 169 | $944K |
| 2 | Vivek Sambhara | Pulmonary Disease | Gainesville, GA | 192 | $792K |
| 3 | Yousof Elgaried | Pulmonary Disease | Pikeville, KY | 128 | $552K |
| 4 | Valery Chu | Pharmacist | Brooklyn, NY | 142 | $546K |
| 5 | Christopher Fanta | Pulmonary Disease | Boston, MA | 122 | $524K |
| 6 | Praveen Akuthota | Pulmonary Disease | San Diego, CA | 51 | $515K |
| 7 | Rebecca Ezell | Nurse Practitioner | Slidell, LA | 130 | $502K |
| 8 | Tiffany Peraino | Physician Assistant | Riverside, CA | 91 | $496K |
| 9 | Sara Keller | Physician Assistant | Rochester, NY | 57 | $428K |
| 10 | Matthew Varner | Pulmonary Disease | Columbia, SC | 99 | $424K |
| 11 | Kartik Shenoy | Pulmonary Disease | Philadelphia, PA | 48 | $367K |
| 12 | Yoel Brito | Pulmonary Disease | Miami, FL | 85 | $366K |
| 13 | Janiece Feuerstein | Nurse Practitioner | Grand Rapids, MI | 99 | $365K |
| 14 | Jitendrakumar Gupta | Pulmonary Disease | Sioux City, IA | 96 | $353K |
| 15 | Albert Mamary | Pulmonary Disease | Philadelphia, PA | 40 | $351K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 171 | Latanoprost (Latanoprost) | $92.3M | 4,388,601 |
| 172 | Ribociclib Succinate (Kisqali) | $90.3M | 5,978 |
| 173 | Lacosamide (Lacosamide) | $90.1M | 300,038 |
| 174 | Mepolizumab (Nucala) | $90.1M | 20,798 |
| 175 | Finerenone (Kerendia) | $89.5M | 93,151 |
| 176 | Ixazomib Citrate (Ninlaro) | $89.0M | 6,901 |
| 177 | Lamotrigine (Lamotrigine) | $89.0M | 1,603,798 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology