Macitentan
Brand name: Opsumit
Rank #47 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$394.6M
Total Cost
30,889
Total Claims
$394.6M
Total Cost
609
Prescribers
$13K
Cost per Claim
2,009
Beneficiaries
31,128
30-Day Fills
$648K
Avg Cost/Provider
51
Avg Claims/Provider
Share of Medicare Part D Spending
0.14%
of total Medicare Part D spending
$394.6M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $394.6M total
🔎 Data Overview
Ranked #47 out of 500 drugs tracked by total cost. Macitentan represents a significant portion of Medicare drug spending.
At $12,776 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $648,000 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $196,432 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Macitentan
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | Hunter Champion | Cardiology | Columbus, GA | 1,052 | $13.4M |
| 2 | Vallerie Mclaughlin | Cardiology | Ann Arbor, MI | 874 | $10.8M |
| 3 | Jean Elwing | Pulmonary Disease | Cincinnati, OH | 665 | $8.5M |
| 4 | Murali Chakinala | Pulmonary Disease | Saint Louis, MO | 595 | $7.7M |
| 5 | Marc Pritzker | Cardiology | Minneapolis, MN | 444 | $5.5M |
| 6 | Ricardo Restrepo-Jaramillo | Pulmonary Disease | Tampa, FL | 397 | $5.0M |
| 7 | Ashwin Ravichandran | Advanced Heart Failure and Transplant Cardiology | Indianapolis, IN | 357 | $4.6M |
| 8 | Barry Rayburn | Internal Medicine | Birmingham, AL | 320 | $4.0M |
| 9 | Peter Engel | Cardiology | Cincinnati, OH | 260 | $3.3M |
| 10 | Christina Eagan | Nurse Practitioner | Gainesville, FL | 253 | $3.2M |
| 11 | Victor Test | Pulmonary Disease | Durham, NC | 227 | $3.1M |
| 12 | Sudarshan Rajagopal | Cardiology | Durham, NC | 226 | $3.0M |
| 13 | Rajan Saggar | Pulmonary Disease | Los Angeles, CA | 237 | $3.0M |
| 14 | Linda Cadaret | Advanced Heart Failure and Transplant Cardiology | Iowa City, IA | 235 | $2.9M |
| 15 | Kimberly Thompson | Nurse Practitioner | New Orleans, LA | 228 | $2.9M |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 44 | Levothyroxine Sodium (Levothyroxine Sodium) | $435.3M | 20,209,418 |
| 45 | Deutetrabenazine (Austedo) | $404.1M | 60,532 |
| 46 | Linagliptin (Tradjenta) | $403.8M | 519,439 |
| 47 | Macitentan (Opsumit) | $394.6M | 30,889 |
| 48 | Insulin Detemir (Levemir Flexpen) | $376.5M | 548,216 |
| 49 | Aripiprazole (Aripiprazole) | $373.1M | 1,494,971 |
| 50 | Apalutamide (Erleada) | $369.2M | 24,956 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology