Ambrisentan
Rank #139 of 500 drugs by total cost
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$117.7M
Total Cost
23,927
Total Claims
$117.7M
Total Cost
709
Prescribers
$4,917
Cost per Claim
1,006
Beneficiaries
24,586
30-Day Fills
$166K
Avg Cost/Provider
34
Avg Claims/Provider
Share of Medicare Part D Spending
0.04%
of total Medicare Part D spending
$117.7M of $275.65B
Top Prescribers by Cost
Top 10 prescribers of $117.7M total
🔎 Data Overview
At $4,917 per prescription, this is a high-cost medication. Expensive drugs drive Medicare spending growth and create access challenges for patients with coverage gaps.
Average cost of $165,946 per prescriber suggests this drug may be concentrated among specialists. High per-provider spending can sometimes indicate inappropriate prescribing or overly aggressive use.
Average cost of $116,954 per patient per year. Medications at this price point significantly impact patient out-of-pocket costs and Medicare spending.
Insights generated from CMS data analysis. Statistical patterns are not accusations — always consider clinical context.
Top Prescribers of Ambrisentan
| # | Provider | Specialty | Location | Claims | Cost |
|---|---|---|---|---|---|
| 1 | R White | Pulmonary Disease | Rochester, NY | 849 | $4.2M |
| 2 | Rahul Argula | Pulmonary Disease | Charleston, SC | 431 | $2.3M |
| 3 | Murali Chakinala | Pulmonary Disease | Saint Louis, MO | 500 | $2.2M |
| 4 | Jean Elwing | Pulmonary Disease | Cincinnati, OH | 257 | $1.3M |
| 5 | Emily Fedewa | Nurse Practitioner | San Francisco, CA | 262 | $1.2M |
| 6 | Denise Sese | Pulmonary Disease | Charleston, SC | 223 | $1.1M |
| 7 | Harrison Farber | Pulmonary Disease | Boston, MA | 258 | $1.1M |
| 8 | Lillian Hansen | Nurse Practitioner | Tucson, AZ | 176 | $1.0M |
| 9 | Eric Roberts | Advanced Heart Failure and Transplant Cardiology | Milwaukee, WI | 204 | $970K |
| 10 | David Badesch | Pulmonary Disease | Aurora, CO | 194 | $920K |
| 11 | Christina Eagan | Nurse Practitioner | Gainesville, FL | 237 | $904K |
| 12 | Michael Mathier | Cardiology | Pittsburgh, PA | 271 | $882K |
| 13 | Ronald Oudiz | Cardiology | Torrance, CA | 150 | $843K |
| 14 | Murali Chakinala | Pulmonary Disease | Saint Louis, MO | 63 | $817K |
| 15 | Mary Whittenhall | Nurse Practitioner | Riverside, RI | 176 | $758K |
Top prescribers ranked by total cost for this drug in 2023.
Related Drugs by Cost
| # | Drug | Total Cost | Claims |
|---|---|---|---|
| 136 | Edaravone (Radicava Ors) | $119.6M | 8,588 |
| 137 | Insulin Regular, Human (Afrezza) | $119.4M | 143,017 |
| 138 | Ezetimibe (Ezetimibe) | $118.1M | 2,859,001 |
| 139 | Ambrisentan (Ambrisentan) | $117.7M | 23,927 |
| 140 | Memantine Hcl (Memantine Hcl) | $117.5M | 2,268,098 |
| 141 | Estradiol (Estradiol) | $115.7M | 1,412,386 |
| 142 | Vortioxetine Hydrobromide (Trintellix) | $113.9M | 197,873 |
Related Analysis
Data from CMS Medicare Part D Prescriber-Drug Public Use File, 2023. Methodology