GLP-1 Receptor Agonists

6 drugs in this class, prescribed by 153,644 Medicare Part D providers.

Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026

Share:

$8.51B

Total Cost

6,297,872

Claims

6

Drugs

$1,352

Avg Cost/Claim

Key Insights

  • Most expensive per prescription: Xultophy 100-3.6 at $1,607/claim
  • Most prescribed: Ozempic with 3,193,643 claims
  • This class represents 3.1% of total Medicare Part D spending

All GLP-1 Receptor Agonists Drugs

DrugCostClaims
Semaglutide$4.30B3,193,643
Dulaglutide$2.99B2,175,100
Tirzepatide$877.9M680,457
Liraglutide$273.0M189,358
Exenatide Microspheres$56.6M48,670
Insulin Degludec/Liraglutide$17.1M10,644

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