SNRIs (Antidepressants)
3 drugs in this class, prescribed by 174,087 Medicare Part D providers.
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$253.7M
Total Cost
7,551,980
Claims
3
Drugs
$34
Avg Cost/Claim
Key Insights
- Most expensive per prescription: Desvenlafaxine Succinate Er at $83/claim
- Most prescribed: Duloxetine Hcl with 5,106,690 claims
- This class represents 0.1% of total Medicare Part D spending
All SNRIs (Antidepressants) Drugs
| Drug | Cost | Claims |
|---|---|---|
| Duloxetine Hcl | $167.7M | 5,106,690 |
| Venlafaxine Hcl | $64.7M | 2,187,710 |
| Desvenlafaxine Succinate | $21.3M | 257,580 |