SSRIs (Antidepressants)
5 drugs in this class, prescribed by 375,603 Medicare Part D providers.
Data: CMS Medicare Part D, 2023 (most current available) · Updated March 2026
$236.4M
Total Cost
18,343,598
Claims
5
Drugs
$13
Avg Cost/Claim
Key Insights
- Most expensive per prescription: Paroxetine Hcl at $16/claim
- Most prescribed: Sertraline Hcl with 6,472,210 claims
- This class represents 0.1% of total Medicare Part D spending
All SSRIs (Antidepressants) Drugs
| Drug | Cost | Claims |
|---|---|---|
| Sertraline Hcl | $74.3M | 6,472,210 |
| Escitalopram Oxalate | $73.6M | 4,975,143 |
| Fluoxetine Hcl | $43.9M | 2,891,768 |
| Citalopram Hydrobromide | $25.3M | 2,778,255 |
| Paroxetine Hcl | $19.2M | 1,226,222 |